Madison, Indiana, circa 1856
Not soon after his arrival in Madison he would marry in 1830 a fellow Swiss emigrant, Anna Bühler from La Neuveville on the Lake of Biel. Anna would give Louis seven children, but would die tragically in the delivery of twins in 1842. Louis would sell the farm in 1848 and would move onto Decatur, Tennessee. In an interesting twist of fate, whether of his own accord or the mistake of a local official, his family name and that of his descendants would become van Buren.
In 1830 Louis would marry Susanna Bühler (1807-1842) daughter of Christian Bühler from Schwanden - Sigriswil in the canton of Bern (1782-1855) and Anna Sahli.
From his wife he had seven children:
1. Lewis van Buren (1831-1886) ∞ Amy Green in 1853.
2. Anna Marie van Buren (1832-?)
3. Margaret van Buren (1834-?) ∞ John Litterer.
4. Augustus (Gus) van Buren (1837-1906) ∞ Mary Ann Ryker.
5. John Adolph van Buren (1839-1921) ∞ Araminta Ryker.
6. Emily van Buren (1841-?) ∞ Frank Litterer.
7. David van Buren (1842-?) ∞ Mary Ledgerwood in 1880.